Ying Liu

Shanghai First Maternity and Infant Hospital

Author Statistics

Papers

Citation

H-Index

i-10 index

Research Trends

Author Order

Document Type

Co-Authors

Lihong Liu

Second Affiliated Hospital of Zhejiang University

Xiangjun Guo

Cangzhou Central Hospital

Yuqin Li

Zunyi Medical University

Li-Ying Sun

Ministry of Education of the People's Republic of China

Zhi‐Jun Zhu

National Clinical Research Center for Digestive Diseases

Lili Guo

Gansu Agricultural University

Zhi‐Gui Zeng

Capital Medical University

Wei Qu

National Clinical Research Center for Digestive Diseases

Xiangli Cui

Capital Medical University

Bin Wang

Tianjin University

Cooperative Institutions

Capital Medical University

Beijing Friendship Hospital

National Clinical Research Center for Digestive Diseases

Tianjin Medical University

Tianjin First Center Hospital

Beijing Chao-Yang Hospital

Capital University

Second Affiliated Hospital of Zhejiang University

China-Japan Friendship Hospital

Zhejiang University

Author Statistics

Papers

Citation

H-Index

i-10 index

Research Field

Feasibility of domino liver transplantation from hyperhomocsyteinemia

Clinics and Research in Hepatology and Gastroenterology (2019)

Wei Qu Zhi‐Jun Zhu Lin Wei Li-Ying Sun Ying Liu

Hyperhomocysteinemia, resulting from a cystathionine beta synthase (CBS) deficiency, is an autosomal recessive disease associated with high levels of homocysteine. Such patients can present with severe mental retardation, ectopia lentis and osteoporosis and thromboembolic disease. To the best of our knowledge, only two cases of liver transplantation for CBS deficiency have been published. Here, we report a case of an 8-year-old male with a CBS deficiency that underwent living donor liver transplantation. The postoperative course was uneventful and homocysteine levels remained normal. The liver of this CBS deficiency patient was then successfully used in domino transplantation. The domino liver transplantation recipient was a 41-year-old male diagnosed with acute liver failure following hemi-liver resection due to cholangiocarcinoma. The domino recipient developed acquired hyperhomocysteinemia, which was controlled with a special regimen of medications. No complications relative to CBS deficiency were observed up to 11 months post-transplant. At this time, the patient expired as a result of cholangiocarcinoma recurrence. In conclusion, our data suggest that liver transplantation for CBS deficiency can be effective, safe and beneficial. It is possible to be both safe and beneficial to use a CBS deficiency patient as a domino donor for salvage liver transplantation in a selective category of recipients.

Hyperhomocysteinemia

Liver disease

10.1016/j.clinre.2019.01.010

Cite

Citations (8)

In vitro comparison of antimicrobial effectiveness of QMix and other final irrigants in human root canals

Scientific Reports (2015)

Ying Liu Lili Guo Yuqin Li Xiangjun Guo Bin Wang

Final root canal irrigation stands as an effective strategy for eliminating the dentin infection. This study aimed to investigate and compare the antibacterial efficacy of QMix and other four final irrigation regimens in reducing Enterococcus faecalis within human root canals. Single-canal human teeth contaminated with E. faecalis for 4 weeks were prepared chemomechanically with sodium hypochlorite (NaOCl). Then, the teeth were randomly assigned into six groups according to the final irrigation protocols: (1) EDTA/NaOCl, 17% EDTA followed by 5.25% NaOCl; (2) EDTA/chlorhexidine (CHX), 17% EDTA followed by 2% CHX; (3) EDTA/cetrimide (CTR), 17% EDTA followed by 2% CTR; (4) MTAD; (5) QMix; and (6) control, 0.9% saline. Bacterial samples collected before instrumentation and after final irrigation were cultured and the colony-forming units (CFUs) were counted. The CFUs in the QMix, EDTA/CHX, and EDTA/CTR groups were significantly lower than those in the EDTA/NaOCl group. No significant differences were observed between the QMix, EDTA/CHX, and EDTA/CTR groups. MTAD showed weaker ability than QMix and EDTA/CHX to eliminate E. faecalis, but it caused a greater reduction in CFU than EDTA/NaOCl. Hence, the antimicrobial activity of QMix was comparable to that of EDTA/CHX and EDTA/CTR and more effective than that of EDTA/NaOCl against intracanal E. faecalis.

Sodium hypochlorite

Enterococcus faecalis

Cetrimide

Ethylenediaminetetraacetic acid

Colony-forming unit

10.1038/srep17823

Cite

Citations (16)

Critical Appraisal of the Quality of Clinical Practice Guidelines for Stress Ulcer Prophylaxis

PLoS ONE (2016)

Zhikang Ye Ying Liu Xiangli Cui Lihong Liu

Inappropriate use of stress ulcer prophylaxis (SUP) is common in many hospitals. High-quality clinical practice guidelines (CPGs) produce better patient outcomes and promote cost-effective clinical care. Thus, the objective of this study was to evaluate the quality of CPGs for SUP.A search was conducted for SUP CPGs using PubMed, Embase, China National Knowledge Infrastructure (CNKI), Chinese Biomedical Literature database (CBM), guideline websites and Google (until March 1, 2015). The quality of CPGs was independently assessed by two assessors using the Appraisal of Guidelines for Research & Evaluation II (AGREE II) instrument, and the specific recommendations in the CPGs were summarized and evaluated.A total of 7 CPGs for SUP were included. The highest median scores were in the clarity of presentation domain (89%), and the lowest median scores were in the editorial independence domain (0%). The rigor of development, stakeholder involvement, and applicability domains all scored below 40%. The specific recommendations for SUP varied, and the recommendations were inconsistent with the supporting evidence.The overall quality of CPGs for SUP was relatively low, and no specific SUP CPG can be recommended. Not only should the AGREE II instrument be used to determine the quality of CPGs, but also the recommendations should be appraised based on supporting evidence, which would contribute to the development of high-quality CPGs.

Guideline

CLARITY

Critical appraisal

10.1371/journal.pone.0155020

Cite

Citations (34)