Yan Rolland

Centre Eugène Marquis

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Magali Rossi

Université Savoie Mont Blanc

Arnaud Pêcher

Laboratoire Bordelais de Recherche en Informatique

Gweltaz Mahéo

École Normale Supérieure de Lyon

Olivier Vidal

Institut des Sciences de la Terre

Stéphane Guillot

Université Gustave Eiffel

Neil S. Mancktelow

ETH Zurich

ÉG

Étienne Garin

Inserm

A. M. Boullier

Institut des Sciences de la Terre

Stéphane Guillot

Centre National de la Recherche Scientifique

Xavier Palard

Centre Eugène Marquis

Cooperative Institutions

Centre National de la Recherche Scientifique

Inserm

Institut de Recherche pour le Développement

Centre Eugène Marquis

Assistance Publique – Hôpitaux de Paris

Université Grenoble Alpes

Université Gustave Eiffel

Institut des Sciences de la Terre

Hôpitaux Universitaires Henri-Mondor

Université de Montpellier

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Recent, climate-driven river incision rate fluctuations in the Mercantour crystalline massif, southern French Alps

Quaternary Science Reviews (2017)

Carole Petit Liran Goren Yan Rolland Didier Bourlès Régis Braucher

Massif

Cosmogenic nuclide

Landform

10.1016/j.quascirev.2017.04.015

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Citations (16)

Prolonged Variscan to Alpine history of an active Eurasian margin (Georgia, Armenia) revealed by 40Ar/39Ar dating

Gondwana Research (2011)

Yan Rolland Marc Sosson S. Adamia Nino Sadradze

Basement

Back-arc basin

10.1016/j.gr.2011.05.007

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Citations (90)

Thermochronology of the highest central Asian massifs (Khan Tengri - Pobedi, SE Kyrgyztan): Evidence for Late Miocene (ca. 8 Ma) reactivation of Permian faults and insights into building the Tian Shan

Journal of Asian Earth Sciences (2020)

Yan Rolland Anthony Jourdon Carole Petit Nicolas Bellahsen Chloé Loury

Thermochronology

Thrust fault

Fission track dating

Massif

10.1016/j.jseaes.2020.104466

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Citations (17)

Exhumation of Neogene gneiss dome between two oblique crustal boundaries in suoth Karakorum (NW, Himalaya, Pakistan).

HAL (Le Centre pour la Communication Scientifique Directe) (2004)

Gweltaz Mahéo Arnaud Pêcher Stéphane Guillot Yan Rolland Christophe Delacourt

Dome (geology)

Neogene

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Citations (3)

Selective internal radiation therapy in older patients with hepatocellular carcinoma: a retrospective analysis

European Journal of Gastroenterology & Hepatology (2021)

Soraya Benguerfi Florian Estrade Céline Lescure Yan Rolland Xavier Palard

Background Selective internal radiation therapy (SIRT) is applied to hepatocellular carcinoma (HCC), a disease with increased incidence in the elderly. However, SIRT has rarely been specifically studied in elderly population. The aim of this study was to investigate efficacy and safety of SIRT in elderly HCC patients. Methods We studied retrospectively data from patients treated with SIRT for HCC. Clinical and laboratory data were retrieved. We used 70-years old as threshold between younger and elderly populations, to compare outcomes. Results A total of 222 patients treated with SIRT for HCC were studied, of which 134 patients were younger and 88 older. Median overall survival (OS) was not significantly different between younger and elderly group: 15.6 months (95% CI, 11.7–19.5) and 14.8 months (95% CI, 9.4–20.3) ( P = 0.86). Age was not associated with OS in multivariable analysis, with a Hazard ratio of 1.09 (95% CI, 0.82–1.45, P = 0.55). Results of progression-free survival and responses were also similar in both groups. Toxicities were similar between the two groups, including the occurrence of radioembolization-induced liver disease (11.5 vs. 11.4%, P = 0.97). Conclusion SIRT appears to be a well-tolerated treatment with the same efficacy in elderly compared to younger patients in HCC. Our study is the first to study its impact with glass microspheres. This warrants confirmation in large prospective studies.

10.1097/meg.0000000000002255

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Citations (4)

Evidence for preHimalayan history and partial Mio-Pliocene reequilibration in the Karakorum Crust ( NW Himalaya) from Ar-Ar amphibole datings.

HAL (Le Centre pour la Communication Scientifique Directe) (2006)

Yan Rolland I.M. Villa S. Guillot Gweltaz Mahéo A. Pêcher

Amphibole

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Citations (0)

Evolution of gravity-driven rock slope failure and associated fracturing: Geological analysis and numerical modelling

Tectonophysics (2011)