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Jiehong Guo

Michigan Technological University

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An Li

Zhejiang University

Shanshan Zhou

Queensland University of Technology

Huan He

Nanjing Normal University

Shiyin Li

Nanjing Normal University

Karl J. Rockne

University of Illinois Chicago

Limin Zhang

Longhua Hospital Shanghai University of Traditional Chinese Medicine

John P. Giesy

University of Saskatchewan

Shaogui Yang

Nanjing Normal University

Marta Venier

Indiana University Bloomington

Neil C. Sturchio

University of Delaware

Cooperative Institutions

Chinese Academy of Sciences

University of Illinois Chicago

Nanjing Normal University

University of Chinese Academy of Sciences

Zhejiang University

Research Center for Eco-Environmental Sciences

Fudan University

State Key Laboratory of Pollution Control and Resource Reuse

Nanjing University

Zhejiang University of Technology

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Temporal and spatial differences in deposition of organic matter and black carbon in Lake Michigan sediments over the period 1850–2010

Journal of Great Lakes Research (2018)

Solidea Bonina Garry Codling Margaret B. Corcoran Jiehong Guo John P. Giesy

Deposition

Sedimentation

10.1016/j.jglr.2018.03.001

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Citations (17)

Bioaccumulation of Dechloranes, organophosphate esters, and other flame retardants in Great Lakes fish

The Science of The Total Environment (2017)

Jiehong Guo Marta Venier Amina Salamova Ronald A. Hites

Bioconcentration

10.1016/j.scitotenv.2016.11.063

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Citations (126)

Occurrence and risk of iodinated X-ray contrast media in source and tap water from Jiangsu province, China

Journal of Hazardous Materials (2022)

Xinying Cheng Yubao Xia Qiuyi Ji Qingsong Ji Huiming Li

Tap water

Iohexol

Water source

10.1016/j.jhazmat.2022.130399

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Citations (13)

Sedimentary records of polychlorinated biphenyls in the East China Marginal Seas and Great Lakes: Significance of recent rise of emissions in China and environmental implications

Environmental Pollution (2019)

Zilan Wu Tian Lin An Li Shanshan Zhou Huan He

China sea

10.1016/j.envpol.2019.112972

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Citations (15)

Exposure to novel brominated and organophosphate flame retardants and associations with type 2 diabetes in East China: A case-control study

The Science of The Total Environment (2023)

Gaoxin Zhang Lingling Meng Jiehong Guo Xiaoling Guan Mei Liu

Triphenyl phosphate

10.1016/j.scitotenv.2023.162107

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Citations (14)

Halogenated carbazoles induce cardiotoxicity in developing zebrafish (Danio rerio) embryos

Environmental Toxicology and Chemistry (2016)

Mingliang Fang Jiehong Guo Da Chen An Li David E. Hinton

Abstract Halogenated carbazoles are increasingly identified as a novel class of environmental contaminants. However, no in vivo acute toxicity information on those compounds was available. In the present study, an in vivo zebrafish embryonic model ( Danio rerio ) was used to investigate the developmental toxicity of those halogenated carbazoles. The results suggested that acute toxicity was structure‐dependent. Two of the 6 tested carbazoles, 2,7‐dibromocarbazole (27‐DBCZ) and 2,3,6,7‐tetrachlorocarbazole, showed obvious developmental toxicity at nanomolar levels. The typical phenotypes were similar to dioxin‐induced cardiotoxicity, including swollen yolk sac, pericardial sac edema, elongated and unlooped heart, and lower jaw shortening. During embryonic development 27‐DBCZ also induced a unique pigmentation decrease. Gene expression and protein staining of cytochrome P4501A (CYP1A) showed that both halogenated carbazoles could induce CYP1A expression at the micromolar level and primarily in the heart area, which was similar to dioxin activity. Further, aryl hydrocarbon receptor‐(AhR)2 gene knockdown with morpholino confirmed that the acute cardiotoxicity is AhR–dependent. In conclusion, the results demonstrate that halogenated carbazoles represent yet another class of persistent organic pollutants with dioxin‐like activity in an in vivo animal model. Environ Toxicol Chem 2016;35:2523–2529. © 2016 SETAC

Danio

Cardiotoxicity

Developmental toxicity

10.1002/etc.3416

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Citations (65)

Accumulation of flame retardants in paired eggs and plasma of bald eagles

Environmental Pollution (2018)

Jiehong Guo Kendall L. Simon Kevin Romanak William W. Bowerman Marta Venier

Bald eagle

Wet weight

10.1016/j.envpol.2018.02.056

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Citations (25)

Mutual interference between 3,6-dichlorinated carbazole and p,p′-dichlorodiphenyltrichloroethane in gas chromatography mass spectrometry analysis

Environmental Monitoring and Assessment (2023)

Shanshan Zhou Qi Su Dan Zhong Jiehong Guo Jinsong Liu

10.1007/s10661-023-11813-6

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Citations (1)

Photochemical degradation of polyhalogenated carbazoles in hexane by sunlight

The Science of The Total Environment (2019)

Shanshan Zhou Xiaoxue Pan Qiaozhi Tang Hongbin Zhu Jiayi Zhou

Sunlight

Hexane

Degradation

10.1016/j.scitotenv.2019.03.325

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Citations (23)

Halogenated flame retardants in sediments from the Upper Laurentian Great Lakes: Implications to long-range transport and evidence of long-term transformation

Journal of Hazardous Materials (2019)

Jiehong Guo Zhuona Li Prabha Ranasinghe Karl J. Rockne Neil C. Sturchio

10.1016/j.jhazmat.2019.121346

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Citations (21)