Gabriel Barg

Universidad Católica del Uruguay

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Elena I. Queirolo

Universidad Católica del Uruguay

Katarzyna Kordas

University at Buffalo, State University of New York

Nelly Mañáy

Universidad de Montevideo

Fabiana Peregalli

Universidad Católica del Uruguay

Gauri Desai

University at Buffalo, State University of New York

Marie Vahter

Karolinska Institutet

Amy E. Millen

University at Buffalo, State University of New York

Ariel Cuadro

Universidad Católica del Uruguay

Gabriela Martínez

Instituto de Ecología

James R. Olson

University at Buffalo, State University of New York

Cooperative Institutions

University at Buffalo, State University of New York

Universidad Católica del Uruguay

New York University

Centro Hospitalario Pereira Rossell

Cornell University

Pennsylvania State University

Karolinska Institutet

Universidad de Montevideo

Universidad de la República

University at Albany, State University of New York

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Blood lead levels and math learning in first year of school: An association for concern

Environmental Research (2024)

Natalia Agudelo Ariel Cuadro Gabriel Barg Elena I. Queirolo Nelly Mañáy

Association (psychology)

Lead (geology)

10.1016/j.envres.2023.118091

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Citations (0)

Pyrethroid and Chlorpyrifos Pesticide Exposure, General Intellectual Abilities, and Executive Functions of School Children from Montevideo, Uruguay

International Journal of Environmental Research and Public Health (2023)

Danelly Rodríguez Gabriel Barg Elena I. Queirolo James R. Olson Nelly Mañáy

Children's developing brains are susceptible to pesticides. Less is known about the effect of exposure to chlorpyrifos and pyrethroids on executive functions (EF). We measured urinary 3,5,6-trichloro-2-pyridinol (TCPy), a metabolite of chlorpyrifos, and urinary 3-phenoxybenzoic acid (3-PBA), a general, nonspecific metabolite of pyrethroids in first-grade children from Montevideo, Uruguay (

10.3390/ijerph20075288

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Citations (2)

Executive functions in school children from Montevideo, Uruguay and their associations with concurrent low-level arsenic exposure

Environment International (2020)

Gauri Desai Gabriel Barg Marie Vahter Elena I. Queirolo Fabiana Peregalli

Arsenic is a known childhood neurotoxicant, but its neurotoxicity at low exposure levels is still not well established. The aim of our cross-sectional study was to test the association between low-level arsenic exposure and executive functions (EF) among children in Montevideo. We also assessed effect modification by arsenic methylation capacity, a susceptibility factor for the health effects of arsenic, and by B-vitamin intake, which impacts arsenic methylation.

Cross-sectional study

10.1016/j.envint.2020.105883

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Citations (26)

A cross-sectional study of general cognitive abilities among Uruguayan school children with low-level arsenic exposure, potential effect modification by methylation capacity and dietary folate

Environmental Research (2018)

Gauri Desai Gabriel Barg Elena I. Queirolo Marie Vahter Fabiana Peregalli

Cross-sectional study

10.1016/j.envres.2018.02.021

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Citations (27)

Secular trends in blood lead concentrations of school-age children in Montevideo, Uruguay from 2009 to 2019

Environmental Pollution (2023)

Elena I. Queirolo Katarzyna Kordas Gabriela Martínez Zia Ahmed Gabriel Barg

Blood lead level

Secular Variation

10.1016/j.envpol.2023.123160

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Citations (3)

Association of Low Lead Levels with Behavioral Problems and Executive Function Deficits in Schoolers from Montevideo, Uruguay

International Journal of Environmental Research and Public Health (2018)

Gabriel Barg Mónica Daleiro Elena I. Queirolo Julia Ravenscroft Nelly Mañáy

The negative effect of lead exposure on children’s intelligence is well-documented. Less is known about the impact of lead on the use of executive functions to self-regulate behavior. We measured blood lead level (BLL) in a sample of first grade children from Montevideo, Uruguay (n = 206, age 6.7 ± 0.5 years, 59.7% boys). Behavior was assessed with teacher versions of the Conners Rating Scale (CRS) and the Behavior Rating Inventory of Executive Functions (BRIEF). Mean BLL was 4.2 ± 2.1 μg/dL; 10% had mild-to-severe ratings of Attentional Deficit with Hyperactivity Disorder (ADHD) (T score > 65). In negative binomial regression, BLL was not associated with CRS sub-scales, but was associated with a poorer ability to inhibit inappropriate behaviors, prevalence ratio (PR) [95% CI]: 1.01 [1.00, 1.03] as measured by the BRIEF. In covariate-adjusted models, the association with BLL was attenuated. When stratified by sex, the covariate-adjusted association between BLL, hyperactivity, poorer inhitibion, emotional control, and behavioral regulation was marginally significant for girls but not boys. In summary, among children with low lead-exposure, we found some, but nonetheless modest, evidence of a relationship between higher BLL and child behavior. If confirmed by larger studies and other objective measures of behavior, such links could have implications for learning and social interaction, particularly among girls.

Blood lead level

Association (psychology)

Attention deficits

10.3390/ijerph15122735

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Citations (27)