Richard J. Heath

St. Jude Children's Research Hospital

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Charles O. Rock

St. Jude Children's Research Hospital

Douglas G. Masson

Seascape Consultants (United Kingdom)

Liang Hao

Institute of High Energy Physics

Irmgard Trummer

GEOMAR Technologie GmbH - GTG

Yi Zhang

Institute of High Energy Physics

M. M. Savalani

Hong Kong Polytechnic University

Matthias Hort

Universität Hamburg

Carmen Jung

Kiel University

Gerhard Bohrmann

University of Bremen

Rock C.

St. Jude Children's Research Hospital

Cooperative Institutions

GEOMAR Technologie GmbH - GTG

Kiel University

National Oceanography Centre

University of Southampton

GEOMAR Helmholtz Centre for Ocean Research Kiel

St. Jude Children's Research Hospital

Institute of High Energy Physics

University of Waterloo

Max Planck Society

University of Tennessee Health Science Center

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Widespread fluid expulsion along the seafloor of the Costa Rica convergent margin

Terra Nova (2002)

Gerhard Bohrmann K. Heeschen Carmen Jung Willi Weinrebe Boris Baranov

Active fluid and gas transport were measured and observed along more than 200 km of the convergent margin of Costa Rica during cruise SO144‐2 aboard RV Sonne . Ten profiles were run with the TV‐sled OFOS, eight of which detected the dense occurrence of cold vent sites. This discovery shows that seafloor fluid expulsion is widely spread along the Pacific margin of Costa Rica. Surficial evidence of fluid expulsion is indicated by the appearance of chemosynthetic vent organisms such as bacterial mats, vesicomyid, solemyid and mytilid bivalves and tubeworms. Numerous active vents were indicated by elevated methane concentrations (≤ 200 nmol L – ) in the bottom water. Although fluid‐venting activity was known previously from a small area south of Nicoya Peninsula, the present study documents active seepage at landslides, headwall scarps related to seamount subduction, morphological intersections of faults and mid‐slope mud volcanoes.

Seamount

Seafloor Spreading

Cold seep

Mud volcano

Chemosynthesis

North American Plate

10.1046/j.1365-3121.2002.00400.x

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Citations (100)

A triclosan-resistant bacterial enzyme

Nature (2000)

Richard J. Heath Charles O. Rock

Pathogenic bacteria

10.1038/35018162

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Citations (282)

Inhibitors of fatty acid synthesis as antimicrobial chemotherapeutics

Applied Microbiology and Biotechnology (2002)

Richard J. Heath Stephen W. White Rock C.

Cerulenin

Fatty acid synthesis

Acetyl-CoA Carboxylase

Natural product

Cysteamine

10.1007/s00253-001-0918-z

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Citations (182)

Erratum: A triclosan-resistant bacterial enzyme

Nature (2000)

Richard J. Heath Charles O. Rock

10.1038/35022656

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Citations (111)

Characterization of selective laser-sintered hydroxyapatite-based biocomposite structures for bone replacement

Proceedings of the Royal Society A Mathematical Physical and Engineering Sciences (2007)

Liang Hao M. M. Savalani Yi Zhang K.E. Tanner Richard J. Heath

Integration of the bone into the implant is highly desirable for the long-term performance of the implant. The development of a bone–implant interface is influenced by the surface morphology and roughness, surface wettability and porosity of the implants. This study characterizes these important properties of a hydroxyapatite-based biocomposite structure fabricated by selective laser sintering (SLS) with a comparison to a moulded specimen. The sintered specimens exhibited a rougher surface with open surface pores and a highly interconnected internal porous structure. It was shown that the characteristics of the powder particles used in the SLS provided a more influential means to modify the surface morphology and the features of the internal pores than laser parameter variation. The correlation of wettability and porous structure shows that although surface open pores could help cell ingrowth and bone regeneration, they resulted in a poorer wettability of the materials, which may not encourage initial cell attachment and adhesion. The potential solution to improve the wettability and cell anchorage is discussed.

Biocomposite

Selective laser sintering

10.1098/rspa.2007.1854

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Citations (28)